06 September 2024
Key Points
Question Do e-cigarettes in flavors selected from a range of appealing options enhance the decreases in cigarette smoking achieved by reducing the nicotine content of combusted cigarettes to minimally addictive levels?
Findings In 3 randomized clinical trials involving 326 participants, decreases in cigarettes smoked daily, resulting from smoking cigarettes with reduced nicotine content, were significantly larger when adults from at-risk populations had access to e-cigarettes in their preferred flavors.
Meaning Findings of this study indicate that access to e-cigarettes in commonly preferred flavors has the potential to enhance the effect of a nicotine-reduction policy on cigarette smoking in populations with psychiatric conditions or lower education level who are at greatest risk for smoking and associated harm.